The Triptych of the Temptation of St. Anthony by Hieronymus Bosch is on display in the Museu Nacional de Arte Antiga, Lisbon.  This puzzle is a one-to-one reporoduction (about 5' by 8' in size) with custom made wood trim.  At the time I purchased it in Paris, this was the largest commercially produced jigsaw puzzle in the world, 12,000 pieces.  It took me and (mostly) my reserach team six months to put it together.